Cagrilintide Peptide – Premium Research Grade

Long-Acting Amylin Analog | ≥99% Purity | HPLC-Tested | Lyophilized Powder

Product Overview

Cagrilintide is a long-acting synthetic amylin analog developed for advanced metabolic and endocrine research. Structurally engineered to mimic and extend the activity of amylin — a pancreatic hormone co-secreted with insulin — Cagrilintide offers researchers a stable, high-purity tool for investigating appetite regulation, satiety signalling, and energy homeostasis pathways.

Its enhanced pharmacological stability compared to native amylin makes it particularly valuable for studies requiring prolonged receptor engagement, allowing more controlled investigation of amylin-related biological mechanisms.

Mechanism of Action

Cagrilintide functions as an amylin receptor agonist, binding to amylin receptors (AMY1–AMY3) to activate downstream signalling pathways. Key areas of research interest include:

Satiety signalling — Amylin plays a well-documented role in post-meal satiety. Cagrilintide allows researchers to study how amylin receptor activation influences appetite suppression pathways and food intake regulation at the cellular level.

Gastric function modulation — Amylin analogs have been studied for their effects on gastric emptying rates. Cagrilintide provides a long-acting model compound for investigating these mechanisms in controlled research settings.

Energy balance research — As part of the broader metabolic hormone axis alongside GLP-1 and insulin, amylin signalling plays a role in energy regulation. Cagrilintide is increasingly studied in combination with GLP-1 receptor agonists for dual-pathway metabolic research.

Research Applications

Cagrilintide is suited for laboratory investigations including:

• Appetite regulation and satiety pathway studies
• Metabolic hormone interaction research
• Gastric emptying and gastrointestinal function analysis
• Endocrine system and pancreatic hormone studies
• Energy homeostasis and obesity-related research models
• Combination studies with GLP-1 analogs such as Semaglutide and Tirzepatide

Product Specifications

Storage & Reconstitution

Store lyophilized Cagrilintide at -20°C for long-term stability or at 4°C if use is planned within 4–6 weeks. Protect from light and humidity at all times. Reconstitute using bacteriostatic water under sterile laboratory conditions. All reconstitution supplies including bacteriostatic water and syringes are available in our accessories category.

Why Order From Graded Peptides

Every batch of Cagrilintide is HPLC-tested to ≥99% purity with documentation available on request. Orders ship across the United States within 24 hours, with discreet and secure packaging. Bulk pricing is available for research institutions — contact us for volume rates.

Frequently Asked Questions — Cagrilintide

What is Cagrilintide used for in research? Cagrilintide is used in laboratory research to study amylin receptor activation, satiety signalling, gastric emptying mechanisms, and metabolic energy balance. It is also increasingly investigated alongside GLP-1 analogs for dual-pathway metabolic research models.

What is the difference between Cagrilintide and native amylin? Native amylin has a short half-life and limited stability, making it less practical for sustained research studies. Cagrilintide is a synthetic analog engineered for prolonged receptor activity and greater formulation stability, making it a more reliable research tool.

Can Cagrilintide be used in combination with other peptides? Yes. Cagrilintide is commonly studied alongside GLP-1 receptor agonists such as Semaglutide and Tirzepatide in metabolic research settings. Graded Peptides supplies all three compounds for combined pathway investigations.

What purity level is your Cagrilintide? Our Cagrilintide is HPLC-tested to ≥99% purity. Certificates of Analysis are available on request for every batch.

How should Cagrilintide be stored? Store at -20°C for long-term stability. For short-term use within 4–6 weeks, refrigeration at 4°C is sufficient. Keep away from light and moisture, and store in a tightly sealed vial until ready for use.

How is Cagrilintide supplied? Cagrilintide is supplied as a lyophilized (freeze-dried) powder for maximum stability during shipping and storage. Reconstitution supplies including bacteriostatic water are available in our accessories category.

For research and laboratory use only. Not intended for human or veterinary consumption. Not for use in the diagnosis, treatment, cure, or prevention of any disease.